2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. Cereblon Isoform
  6. Cereblon Modulator

Cereblon Modulator

Cereblon Modulators (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-130800
    Eragidomide 1860875-51-9 99.76%
    Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation.
    Eragidomide
  • HY-146237
    Golcadomide 2379572-34-4
    Golcadomide (CC-99282) is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). Golcadomide co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. Golcadomide can be used for researching non-Hodgkin lymphomas.
    Golcadomide